Mr Ralph Murphy graduated from Imperial College, London in 2011 and moved back up north to his home town of Manchester where he began my academic plastic surgery training. He undertook lab-based research into peripheral nerve regeneration as part of his academic foundation programme based at the Universities of Manchester and Umeå (Sweden) under the tutelage of Mr. Adam Reid, Professor Terenghi and Professor Wiberg. After his first year of specialist training he applied to an NIHR-funded clinical fellowship helping to run a first-in-man clinical trial of a new nerve conduit device as associate P.I. working under the guidance of Mr. Reid. He have subsequently been awarded an EPSRC/MRC PhD studentship at the University of Manchester looking to develop novel outcome measures for peripheral nerve regeneration.
Biography: Mr Matthew Gardiner
Matthew Gardiner is a consultant plastic and hand surgeon and the new Surgical Specialty Lead for Plastic and Hand Surgery. He is passionate about collaborative clinical research. He co-founded the Reconstructive Surgery Trials Network, with Prof. Abhi Jain, and until recently was the trainee lead. Read more.
Biography: Professor Mikael Wiberg
Professor Wiberg has nearly 30 years experience in the field of reconstructive surgery with focus on mainly congenital malformations and nerve reconstruction. He has worked scientifically within these areas for nearly 40 years in Uppsala, Umeå and the last 20 years also within UK. He has a wide national and international network both clinically and scientifically. His work and scientific production played an important role when Umeå for the first time got national responsibility (Rikssjukvård) together with Stockholm for major nerve injuries (brachial plexus injuries) . Wiberg is a member since the start of the National Board for Cell, Tissue, Organ and Blood (Nationella Vävnadsrådet) and its subgroup for Celltherapy. He is also a Board Member of the National Board of Health care and Social welfare (Socialstyrelsen) and The Swedish Governments expertgroup for Life Sceince. Prof Wiberg has a total of 125 peer reviewed original articles in Pubmed mainly within the area of nerve reconstructive surgery.
Biography: Professor Jagdeep Nanchahal
Jagdeep Nanchahal
Professor of Hand, Plastic and Reconstructive Surgery
Jagdeep Nanchahal is a surgeon scientist focussing on defining the molecular mechanisms of common diseases and translating his findings through to early phase clinical trials.
He undertook his PhD, funded by the MRC, whilst a medical student in London and led a lab group funded by external grants throughout his surgical training. After completing fellowships in microsurgery and hand surgery in the USA and Australia he was appointed as a senior lecturer at Imperial College. His research interests complement his clinical practice and he first became associated with the Kennedy Institute through his research on patients with rheumatoid arthritis, where his group showed that cytokine inhibition would be effective for controlling tenosynovitis.
His research is now focussed on promoting tissue regeneration by targeting endogenous stem cells and reducing fibrosis. In 2013 his group identified TNF as therapeutic target for Dupuytren’s disease, a common fibrotic condition of the hand. He is currently leading a phase 2b clinical trial funded by the Wellcome Trust and Department of Health to assess the efficacy of local administration of anti-TNF in patients with early stage Dupuytren’s disease. In collaboration with the Structural Genomics Consortium his group are investigating the epigenetic regulation of myofibroblasts in Dupuytren’s disease. His group has also identified a novel mechanism for promoting repair and regeneration of multiple tissues by targeting endogenous stem cells.
He is a proponent of evidence-based medicine and was the only plastic surgery member of the NICE Guidance Development Groups on complex and non-complex fractures. He is co-applicant on a trial led by Prof Matt Costa, Kadoorie Centre, NDORMS, investigating the efficacy of negative pressure wound therapy on closed incisions following orthopaedic trauma.
You can read more here.
National Plastic Surgery Research Forum Meeting Programme 6th July 2019
Saturday 6th July 2019, Royal Free Hospital, Pond Street, London, NW3 2QG
Venue: Peter Samuel Hall, 1st Floor
Provisional Programme:
8:30-8:45: Registration, Tea & Coffee
Session: Introduction and academic plastic surgery
8:45-8:50: Professor Ash Mosahebi: Welcome
8:50-9:00: Mr Mark Henley: Opening of forum
9:00-9:20: Professor Peter Butler: Setting up a National Facial Transplant Program: Hurdles, pitfalls, triumphs and failures
9:20-9:40: Professor Andrew Hart: Building a career in academic plastic surgery, reflections on one route
Session: Artificial intelligence in surgery
9:40-10:00: Professor Naiem Moiemen: AI Surgeons’ Perspective
10:00-10:20: Mr Allan Ponniah: Using artificial intelligence for facial reconstruction
10:20-10:50: Tea & Coffee
Session: Nerve and vascular surgery
10:50-11:10: Professor Mikael Wiberg: The use of stem cells in reconstructive nerve surgery. Dream or reality?
11:10-11:30: Mr Ralph N. A. Murphy: Peripheral nerve regeneration including our first-in-man polymer nerve conduit trial
11:30-11:50: Professor George Hamilton: Outcomes from modern management of Vascular Malformations
11:50-12:10: Dr Amir Gander: A platform to bridge the gap between basic research and clinical trials
12:10-13:30: Lunch break
Session: Aesthetic surgery
13:30-13:50: Associate Professor Eqram Rahman: ‘Let there be light’: Evidence based practice and current research in non-surgical aesthetics
13:50-14:10: Dr Katie Goldie: Optimising soft tissue filler placement – full face approach
14:10-14:30: Professor Katarina Andjelkov: The role of Stromal Vascular Fraction cells and signalling proteins in the treatment of Androgenetic Alopecia
Session: Clinical Trials
14:30-14:45: Mr Matthew Gardiner: Where next for clinical trials in plastic and hand surgery?
14:45-15:05: Professor Kurinchi Gurusamy: All systematic reviews are not created equal
15:05-15:30: Tea & Coffee
15:30-15:50: Mr Dan Marsh: Gamma delta T cells – a novel cancer therapy
Session: Tissue engineering in plastic surgery
15:50-16:10: Professor Wenhui Song: 3D printing elastomer nanohybrid for soft tissue reconstruction
16:10-16:30: Associate Professor Deepak Kalaskar: Improving implant interface to facilitate tissue integration and angiogenesis
16:30-16:35: Closure, Professor Ash Mosahebi
16:35: Drinks & Nibbles
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